Donna Karan launched her infamous fashion brand back in 1985 with her line of practical clothing for women. Twenty-five years later, Donna Karan Inc. now also includes the Donna Karan lines and the younger DKNY line, along with accessories, eyewear, intimates, fragrances, home collections, and more. A native of Long Island, Karan has always maintained that …

He’s in charge of four powerhouse fashion labels: The Marc Jacobs Collection, Marc by Marc Jacobs, Little Marc, and Louis Vuitton (he’s their creative director), but this NYC born designer doesn’t seem overwhelmed. Instead, the Marc Jacobs empire continues to expand, first with the launch of its e-commerce store at marcjacobs.com, and then with Bookmarc, a …

Over the past 25 years, the eponymous Tommy Hilfiger brand has taken a vision of classic American sportswear and made it into one of the world’s most recognized lifestyle brands. Today, there are more than 1,000 Tommy Hilfiger stores worldwide, with plans to continue to expand into new markets in the coming years.

2010 marks the ten-year anniversary of her flagship store on Madison Avenue and this luxury fashion designer is showing that she’s still going strong. In September, she was named the Mercedes-Benz Presents designer for New York’s Spring/Summer 2011 fashion week. Her most recent venture includes a newly launched fragrance: 212 VIP.

Formerly the creative director of Gucci, for which he is credited with turning the almost-bankrupt fashion house into an empire valued at $4.3 billion upon his departure. He now heads the eponymous Tom Ford fashion label, which boasts 21 freestanding stores throughout the world. Ford is famous for dressing some of Hollywood’s hautest leading men including …