Lore Harp could be considered nothing short of a driven genius. She serves as the chairman of the Board of Associates for MIT’s Whitehead Institute for Biomedical Research, and serves on the board of advisors for a slew of other entities. As if that weren’t daunting and impressive enough, she is also a strategic advisor …

Fake is an art director; Butterfield is a Web designer. The two of them are hailed as Web 2.0 geniuses, thanks to their photo-sharing site Flickr, which they launched in 2004 without a dime of investments from venture capitalists. Just 16 months later, Yahoo! wrote a check to the power couple to the tune of …

He’s a co-founder of Google—need we say more? She partnered with Linda Avery to found 23andMe, a company that profiles personal genetics to help determine the role that genes play in everyone’s lives. Google provided a bit of the start-up capital for this venture. Brin, who was president of technology at Google from 2001-2011, now …